The 5th edition of the Spinoff Conference 2025 will gather over 400 speakers, guests, and ecosystem leaders, alongside 40 breakthrough spinoff teams, creating one of Europe’s most vibrant arenas for deep-tech innovation. The event brings together researchers, entrepreneurs, investors, corporates, clusters, and policymakers, forming a powerful engine for transforming scientific discoveries into scalable ventures.
As a central platform in the European innovation landscape, the conference drives progress across health and biotechnology, clean technology, artificial intelligence, microelectronics, and cybersecurity, supporting cross-sector collaboration and accelerating the adoption of next-generation technologies.
With a bold vision for the future, the Spinoff Initiative is committed to enabling the creation and growth of 500+ new spinoffs by 2030, strengthening Europe’s competitiveness and shaping the future of science-based entrepreneurship.
The Spinoff EUROPA 2026 conference addresses spinoff founders, researchers, investors, academia, policymakers, industry leaders, clusters, European Digital Innovation Hubs (EDIHs), public scientific and research infrastructures, and innovation ecosystem actors engaged in scaling deep-tech solutions across Europe.
We invite innovative teams to apply for the Spinoff of the Year 2026 award and showcase their excellence at the Spinoff EUROPA Conference 2026.
Eligible projects must have successfully passed at least Technology Readiness Level (TRL) 2, with work already initiated on TRL 3 (Proof of Concept) in an experimental environment.
Proposed innovations must fall within one or more of the following priority areas: biotechnology, health, food technology, semiconductors and chips, artificial intelligence, cybersecurity, and virtual or augmented reality (VR/AR).
Projects will be evaluated based on the team's expertise and capacity, the solution's maturity and innovativeness, its competitive positioning, market relevance, business potential, and the completeness of the submitted documentation. Expected results must be clear, measurable, realistic, and logically linked to the planned activities.
👉 Apply now via the Spinoff Award Application Form
Corporate Spinoff
University Spinoff
Academy Spinoff
Government Spinoff
Campaign period:
10 Jan 2026 - 8 May 2026
Dates: 5–9 June 2026 I Time: 14:00 – 18:00 (CET) I Format: Hybrid (On-site & Online)
Embedded in the PRECISEU European Innovation Valley, the Personalised Medicine School serves as a preparatory platform, equipping participants with the skills and insights needed to develop spinoffs and participate actively in Spinoff EUROPA 2026.
Participants will have the unique opportunity to:
Engage in exclusive, interactive sessions with experts from EMA, EPerMed, EATRIS, VELES, and European AI Factory initiatives
Work alongside innovators preparing real spinoff pitches for the Spinoff EUROPA Conference
Learn how to translate clinical, genomic, and real-world data into actionable innovation and commercialisation roadmaps
Explore how European policy frameworks (EHDS, ATMP regulation, AI Act) shape adoption in healthcare
Connect directly with industry, clusters, investors, policymakers, and European innovation ecosystems
Doctoral students and early-career researchers
Clinicians and healthcare innovators
Entrepreneurs and spinoff teams
Innovation managers and technology transfer professionals
Policy and ecosystem stakeholders involved in personalised medicine
Gain insights into cutting-edge European initiatives and regional partnerships.
Understand the opportunities and challenges of ATMPs and data-driven personalised medicine
Learn how health data and AI enable discovery, validation, and scale-up
Acquire early exposure to innovation, investment, and spinoff pathways
Become part of the Spinoff EUROPA 2026 innovation community.
Participants attending at least three sessions will receive a certificate of participation, recognising their commitment to advancing personalised medicine competencies.
Join us in Sofia to shape the next generation of personalised medicine—where science, data, and innovation turn into real impact.
16:00 - 19:00 Sofia walking tour
Provided by Invest Sofia agency
Starting point: Patriarchal Cathedral "St. Alexander Nevsky" - visit inside (for 15-20 minutes) and movement along the route: Cathedral "St. Sophia", ul. "Moskovska", the Palace, the National Theater, the Triangle of Power, the shortest ul. "Malko Tarnovo", the Presidency, the Late Antique Temple - Rotunda "St. George", Cathedral "St. Nedelya", Ancient Serdica, Largo, passing through the Quadrangle of Tolerance, the Tourist Information Center "Tram - 83" is indicated (with the opportunity to enter, view, receive advertising materials for Sofia and take pictures after the end of the tour).
End point: in front of RIM - Sofia (the building of the former Central Mineral Bath in Sofia) and the mineral springs nearby are shown ( with support of Sofia Tourism Administration )
Please note that the agenda may change!
9:00 – 9:30
Registration Spinoff Europa Conference 2026 & Morning Coffee
9:35 – 10:00
Official Guest Speaker
10:40 - 11:20
Panel 1: Building Europe’s Innovation Valley for Personalised Medicine
PRECISEU – Innovation Valley for Personalised Medicine
The general objective of PRECISEU is to increase the efficiency of the regional innovation ecosystems through strengthened collaboration and shared resources on strategic areas of regional strength and specialisation, enabling the development and implementation of innovating initiatives, and facilitating the digital and sustainable transformation of the healthcare systems PRECISEU consortium has broken down this complex general objective (GO) into four core elements, representing the building blocks of the project.
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11:40 - 12:20
Panel 2: From Strategy to Deployment: European Health Data Space Initiatives
VELES Excellence Hub
On June 1, 2023, under the HORIZON-WIDERA-2022-ACCESS-04 (Excellence Hubs) initiative, the VELES Excellence Hub was launched. The mission is to elevate innovation excellence in South-East Europe by establishing a sustainable place-based innovation ecosystem, powered by the Regional Smart Health Data Space.
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12:20 - 12:40
Keynote: The European Medicines Agency (TBC)
12:20 - 13:00
Fireside Chat: Unlocking the Dual Use of Health Data for Care, Research and Innovation
A focused conversation on enabling both primary and secondary use of health data, balancing innovation, trust, and regulatory safeguards.
14:00 - 14:30
Keynote: Shaping Europe’s Health Innovation Landscape through Horizon Europe
Powered by: National Contact Points (NCPs) for Horizon Europe. An overview of how Horizon Europe supports health and digital innovation, from research to deployment, and its role in strengthening Europe’s innovation ecosystem.
15:00 - 16:00
ENACT – Advancing Biotech for Better Health.
Funded under Horizon Europe, ENACT brings together a pan-European consortium to develop innovative biotech solutions that enhance healthcare delivery and outcomes. With a strong focus on stakeholder collaboration and data-driven insights, the project aims to translate cutting-edge research into real-world health impact across diverse European regions.
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InnoMedCatalyst – Accelerating 5P Digital Health Innovation
InnoMedCatalyst is an EU-funded initiative under the I3 Programme, uniting 13 partners from Romania, Poland, Bulgaria, Belgium, Italy, Spain, Greece, and Portugal. The project aims to enhance regional innovation capacity in 5P medicine—predictive, Preventive, Personalised, Participative, and precise — by supporting 36 startups and entrepreneurs through acceleration programs, mentorship, and open innovation platforms. By 2026, it seeks to develop over 20 investment-ready digital health projects, fostering collaboration between MedTech companies and healthcare providers across Europe.
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European Partnership OHAMR
The European Partnership One Health Antimicrobial Resistance (EUP OHAMR) aims to develop innovative solutions through interdisciplinary research to advance the management of antimicrobial resistance challenges. The first call for proposals for this joint research program between the European Commission and the member states will be launched in November 2025.
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11:00 - 11:20
Fireside Chat: The European AI Innovation Landscape – Perspectives from the European AI Forum (EAIF)
Powered by: European AI Forum (EAIF) - the umbrella organisation of national European AI associations and clusters, representing over 3000 of innovators, companies and experts to connect AI ecosystems and advocate jointly on policy, innovation and ecosystem development across Europe. https://eaiforum.org/
Main Conference - Inspirational talks, discussions, panel sessions
B2B Matchmaking & Horizon Europe Partnerships
Workshops: 360-degree Labs for: Personalized Medicine, Clean Tech, AI adoption, Cybersecurity
Triple AI Zone – A dedicated space for attendees to engage in fun and intuitive AI prompt learning, experiment with AI-generated content, and explore real-world AI applications.
CyberTech Zone
Spinoff Showcases
Spinoff of the Year Award Ceremony
Round Table Discussions
Become part of a growing European movement that champions innovation, entrepreneurship, and research commercialisation.
By signing the Spinoff Europa initiative Declaration, your organisation shows its commitment to fostering science-based entrepreneurship and helping transform research into real-world impact.
Sign up your organisation to:
Join a vibrant, cross-sector European network
Support spinoff creation and scaling
Access collaboration, visibility, and policy-shaping opportunities
Be part of shaping Europe’s innovation-driven future
🔗 Sign the Spinoff Europa initiative Declaration and make your commitment official.
6th edition Spinoff Europa Conference 2027 / 17 - 18 June 2027
7th edition Spinoff Europa Conference 2028 / 15 - 16 June 2028
8th edition Spinoff Europa Conference 2029 / 21 - 22 June 2029
9th edition Spinoff Europa Conference 2030 / 20 - 21 June 2030